From the middle of 1970s development of biotechnological and bioengineering methods takes more and more important position among other biological discipline, although the use of biological objects in the several industrial branches is far from new idea. So baking, brewing, wine making, dairy have been grounding on the using of microorganisms for a long time.

During the more than thirty years of these discipline development scientists have been succeeded in knowledge, methods and experimental data accumulation. However the elaboration of growing information flow becomes increasingly difficult in the last years. As a result of that Systems biology and concerned research take on significant role because methods which are using in this field of biological knowledge are able to be instruments of structuring and systematization of accumulated information.

In our research work applied research in the field of bioengineering and biotechnology take significant place. Currently it is possible to distinguish in this sphere two directions. The first one is a bioengineering direction based on strain improvement for the yield increase of final product, the second is biotechnological direction, which is connected with increase of productive efficiency indusitrial processes.