The mature multicellular organism in extremely well-ordered system, every part of that (cell) may be classified on type in compliance with the performed function and defined morphology. In spite of the fact that all cells (excluding germ cells) in the organism contain identical genetic information, defined group of genes may be blocked in them that define difference in various cell types functioning. Great number of research have demonstrated that, as a rule, mature cells are not be able to change their specialization, and a lot of cell types even can not divide.

Nevertheless replenishment of defined types cells (arising as a result of injury, organism growth, or natural renewal) is always required in any organism during vital functions, and mechanism of mature cells formation should exist. Practically in all higher organisms such mechanisms are realized by consistent conversion (differentiation) of special cell type, being able to divide at no allowance and to transform in other cells. Such non varied cells, giving the origin to other types, are named steam and presents in all organisms.

It is possible to consider presented research as first step of our group on the way of apoptosis research and, more exactly – their antagonist – antiapoptosis. We have reconstructed pathways of NFkB-dependent transcription activation - the main process defined antiapoptotic response. In the future exactly this research allowed us to start detailed kinetic model of one of the main unit of these processes.