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Kinetic modeling is the part of systems biology; its aim is to describe dynamic processes, going into the cells. The basis of kinetic model is the system of mechanistic ordinary differential equations, which, as a rule is stiff and nonlinear, therefore numerical methods are used for system analysis. The system of equations of kinetic model has a great number of parameters, their quantitative values being estimated from experiments, various numerical optimization methods are used for their estimation. The model developed by such way allows leading the comprehensive analyze of phenomena existent in the cell and to reply many researchers’ questions. Increasing interest to the kinetic modeling is determined by applied program development as well, permitting to the researcher to concentrate on the direct creation of biological model. On the web site http://www.sbml.org/ are presented the program packet for creation and analysis of kinetic models. All the programs presented on the web site support the unified data format SBML, allowing making the model exchange between packets. You can freely download the lates versions of software packages from our website. |
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| 1. | DBSolve Manual (Software/DbSolve Optimum) | 239 |
| 2. | Introduction to systems pharmacology modeling and its possible applications to drug discovery and development (Information materials/Workshops) | 120 |
| 3. | Kirill Peskov "Kinetic modeling of Escherichia coli central carbon metabolism" (Publications/Abstracts of Ph.D. thesises) | 110 |
| 4. | ISBSPb Results and Experience (Information materials/Presentations) | 94 |
| 5. | Материалы к учебному курсу "Моделирование в системной биологии и биомедицине" (Information materials/Workshops) | 79 |
| Курс "Введение в кинетическое моделирование для фармакологии" Tuesday, 13 September 2011 |
| Учебный курс "Моделирование в системной биологии и биомедицине" Tuesday, 12 April 2011 |
| 28 марта на семинаре ИСБСПб выступит Дмитрий Алексеев Thursday, 03 March 2011 |
| Collection of signatures under young scientists open letter about 94-FZ law Wednesday, 02 March 2011 |
| The ISBSPb conference 2011 Tuesday, 08 February 2011 |
| Oksana Galzitskaya will present lecture at ISBSPb seminar on the 31th of January Wednesday, 26 January 2011 |
| Merry Christmas and Happy New Year!!!! Friday, 31 December 2010 |
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Institute for Systems Biology SPb Moscow, Leninskie Gory, 1, build.75G, office. 613, Science park, 119992 |